60 days in South America Itinerary

60 days in South America Itinerary

Created using Inspirock South America vacation builder
Make it your trip
Fly
1
Cartagena, Colombia
— 5 nights
Fly
2
San Andres Island, Colombia
— 7 nights
Fly
3
Medellin, Colombia
— 4 nights
Fly
4
Bogota, Colombia
— 5 nights
Fly
5
Quito, Ecuador
— 6 nights
Fly
6
Cuenca, Ecuador
— 2 nights
Drive
7
Guayaquil, Ecuador
— 3 nights
+2
Fly to Baltra Island, Fly to San Cristobal, Ferry to Puerto Ayora
8
Puerto Ayora, Ecuador
— 9 nights
+2
Bus to Santa Cruz Ferry Terminal, Ferry to Isla Baltra Ferry Terminal, Fly to Asuncion
9
Asuncion, Paraguay
— 5 nights
Taxi to Ypacaraí, Bus to Ciudad Del Este
10
Ciudad Del Este, Paraguay
— 4 nights
+2
Bus to Foz do Iguacu, Fly to Boa Vista, Drive to Iwokrama Forest
11
Iwokrama Forest, Guyana
— 1 night
Taxi to Lethem, Fly to Georgetown
12
Georgetown, Guyana
— 8 nights
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Cartagena, Colombia — 5 nights

The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
You'll find plenty of places to visit near Cartagena: Isla Baru (Aviario Nacional de Colombia & Playa Blanca). There's lots more to do: step into the grandiose world of Castillo de San Felipe de Barajas, make a trip to Plaza de Bolivar, take in the spiritual surroundings of Convent of Santa Cruz de la Popa, and take in the local highlights with Walking tours.

For reviews, where to stay, other places to visit, and tourist information, read Cartagena online travel planner.

Charlotte, USA to Cartagena is an approximately 9.5-hour flight. Traveling from Charlotte in April, you will find days in Cartagena are somewhat warmer (90°F), and nights are warmer (78°F). Cap off your sightseeing on the 26th (Tue) early enough to catch the flight to San Andres Island.
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Historic Sites · Tours · Parks · Outdoors
Side Trip
Find places to stay Apr 21 — 26:

San Andres Island, Colombia — 7 nights

The coral San Andres Island boasts a rich colonial history, exotic beaches, and a laidback, tropical lifestyle.
San Andres Island is known for nature, wildlife, and parks. Your trip includes some of its best attractions: step off the mainland to explore Johnny Cay, kick back and relax at Playa de San Luis, see some colorful creatures with Blue Life Centro de Buceo, and make a trip to Cayo Rocoso.

To find other places to visit, photos, traveler tips, and tourist information, read San Andres Island route builder website.

Traveling by flight from Cartagena to San Andres Island takes 3 hours. In April in San Andres Island, expect temperatures between 87°F during the day and 78°F at night. Finish up your sightseeing early on the 3rd (Tue) so you can catch the flight to Medellin.
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Parks · Outdoors · Beaches · Nature
Find places to stay Apr 26 — May 3:

Medellin, Colombia — 4 nights

Nestled between rising hills in a narrow valley, Medellin serves as an energetic melting pot of people from all socio-economic classes.
Medellin is known for sightseeing, parks, and museums. Your trip includes some of its best attractions: take in the local highlights with Walking tours, head outdoors with Outdoor Activities, stroll through Parque Arvi, and steep yourself in history at Pueblito Paisa.

To find photos, other places to visit, reviews, and tourist information, read Medellin driving holiday planner.

You can fly from San Andres Island to Medellin in 3.5 hours. In May, Medellin is slightly colder than San Andres Island - with highs of 82°F and lows of 64°F. Finish your sightseeing early on the 7th (Sat) to allow enough time to fly to Bogota.
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Parks · Tours · Zoos & Aquariums · Outdoors
Find places to stay May 3 — 7:

Bogota, Colombia — 5 nights

Colombia's heart and soul, Bogota has earned the nickname "Athens of South America" thanks to its abundance of universities, libraries, and lower-level schools.
Explore the numerous day-trip ideas around Bogota: Zipaquira (Catedral de Sal de Zipaquira & Desal) and Chingaza National Park (in Fomeque). And it doesn't end there: explore the world behind art at Museo Botero del Banco de la Republica, test your problem-solving skills at popular escape rooms, let your taste buds guide you at a local gastronomic tour, and examine the collection at Museo Nacional de Colombia.

You can plan Bogota trip in no time by asking Inspirock to help create your itinerary.

Traveling by flight from Medellin to Bogota takes 2.5 hours. Alternatively, you can drive; or take a bus. Traveling from Medellin in May, expect Bogota to be slightly colder, temps between 67°F and 50°F. Wrap up your sightseeing on the 12th (Thu) to allow time to fly to Quito.
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Nature · Parks · Museums · Historic Sites
Side Trips
Find places to stay May 7 — 12:

Quito, Ecuador — 6 nights

High in the Andean foothills, Quito remains one of the world's most photogenic capital cities, featuring two dramatic mountain ranges as its backdrop.
Explore the numerous day-trip ideas around Quito: Termas de Papallacta (in Papallacta), Cuicocha (in Cotacachi) and Cascada de Peguche (in Peguche). And it doesn't end there: get engrossed in the history at Museo Templo del Sol Pintor Ortega Maila, explore the world behind art at Casa Museo Guayasamin, gain insight at La Ronda, and appreciate the extensive heritage of Quito Old Town.

To find other places to visit, ratings, more things to do, and tourist information, use the Quito travel site.

Traveling by flight from Bogota to Quito takes 5 hours. Alternatively, you can drive; or take a bus. Plan for somewhat warmer nights when traveling from Bogota in May since evenings lows in Quito dip to 61°F. Wrap up your sightseeing on the 18th (Wed) to allow time to fly to Cuenca.
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Museums · Historic Sites · Nature · Parks
Side Trips
Find places to stay May 12 — 18:

Cuenca, Ecuador — 2 nights

Packed with impressive colonial architecture and a historic town center, Cuenca stands as perhaps the most charming city in the nation.
On the 19th (Thu), see the interesting displays at Museo del Sombrero de Paja Toquilla, explore the wealth of natural beauty at El Cajas National Park, and then explore the activities along Laguna La Toreadora. Here are some ideas for day two: admire the striking features of Inmaculada Concepción Cathedral, examine the collection at Museo Catedral Vieja, and then take in the architecture and atmosphere at Mirador de Turi.

Plan my day in Cuenca using traveler tips and tourist information provided by Inspirock.

You can fly from Quito to Cuenca in 2.5 hours. Other options are to drive; or take a bus. Traveling from Quito in May, expect slightly colder with lows of 53°F in Cuenca. Cap off your sightseeing on the 20th (Fri) early enough to go by car to Guayaquil.
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Historic Sites · Museums · Nature · Parks
Find places to stay May 18 — 20:

Guayaquil, Ecuador — 3 nights

Hills dotted with colorful houses and waterfront promenades typify Guayaquil, Ecuador's largest city and commercial center.
Guayaquil is known for sightseeing, historic sites, and parks. Your trip includes some of its best attractions: appreciate the extensive heritage of Guayaquil Historical Park, take in the waterfront at Malecon 2000, take a stroll through Cerro Santa Ana, and visit Las Penas.

To see where to stay, reviews, and other tourist information, refer to the Guayaquil vacation app.

You can drive from Cuenca to Guayaquil in 3.5 hours. Alternatively, you can take a bus. When traveling from Cuenca in May, plan for somewhat warmer days and much hotter nights in Guayaquil: temperatures range from 88°F by day to 74°F at night. Wrap up your sightseeing by early afternoon on the 23rd (Mon) to allow enough time to travel to Puerto Ayora.
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Parks · Neighborhoods · Historic Sites · Wildlife
Find places to stay May 20 — 23:

Puerto Ayora, Ecuador — 9 nights

The largest settlement in the Galapagos, Puerto Ayora offers visitors to the islands an array of facilities and things to do.
Step out of Puerto Ayora to go to Baltra and see North Seymour Island, which is approximately 1h 20 min away. There's much more to do: stroll through Charles Darwin Research Station, view the masterpieces at The Angelique Art Gallery, see some colorful creatures with a scuba or snorkeling tour, and stroll around El Garrapatero.

To see where to stay, more things to do, traveler tips, and other tourist information, you can read our Puerto Ayora trip itinerary planning app.

Getting from Guayaquil to Puerto Ayora by combination of flight and ferry takes about 9 hours. Expect a daytime high around 84°F in May, and nighttime lows around 75°F. Wrap up your sightseeing on the 1st (Wed) early enough to travel to Asuncion.
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Parks · Outdoors · Beaches · Museums
Side Trips
Find places to stay May 23 — Jun 1:

Asuncion, Paraguay — 5 nights

Paraguay's capital and economic center, Asuncion ranks among the youngest cities on the continent, with more than half of its residents under 30 years of age.
Explore the numerous day-trip ideas around Asuncion: Castillo Carlota Palmerola (in Aregua), Lago Ypacarai (in San Bernardino) and Eco Reserva Mbatovi (in Paraguari). The adventure continues: steep yourself in history at Casa de la Independencia, don't miss a visit to Costanera de Asuncion, admire the masterpieces at Museo Etnografico Andres Barbero, and learn about wildlife with up-close encounters at Botanical Garden and Zoo (Jardin Botanico y Zoologico).

To find photos, where to stay, reviews, and tourist information, refer to the Asuncion online travel planner.

Traveling by combination of bus, ferry, and flight from Puerto Ayora to Asuncion takes 18.5 hours. Alternatively, you can do a combination of ferry and flight. Traveling from Puerto Ayora to Asuncion, you'll lose 1 hour due to the time zone difference. Plan for little chillier temperatures traveling from Puerto Ayora in June, with highs in Asuncion at 72°F and lows at 56°F. Finish your sightseeing early on the 6th (Mon) to allow enough time to travel to Ciudad Del Este.
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Museums · Parks · Historic Sites · Wildlife
Side Trips
Find places to stay Jun 1 — 6:

Ciudad Del Este, Paraguay — 4 nights

The commercial center of eastern Paraguay, busy Ciudad Del Este serves primarily as a shopping destination for Argentines and Brazilians.
When in Ciudad Del Este, make a side trip to see Refugio Tati Yupi in Hernandarias, approximately Hernandarias away. The adventure continues: admire the sheer force of Saltos del Monday, identify plant and animal life at Parque Aventura Monday, make a trip to PRESA DE ITAIPU, and head outdoors with Lago de la Republica.

To see photos, traveler tips, where to stay, and tourist information, go to the Ciudad Del Este trip itinerary builder app.

Getting from Asuncion to Ciudad Del Este by combination of taxi and bus takes about 4.5 hours. Other options: drive; or take a bus. The time zone changes from Paraguay Standard Time (PYT) to Brasilia Standard Time (BRT), which is usually a 1 hour difference. In June, daily temperatures in Ciudad Del Este can reach 71°F, while at night they dip to 55°F. Finish up your sightseeing early on the 10th (Fri) so you can travel to Iwokrama Forest.
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Parks · Outdoors · Shopping · Nature
Side Trips
Find places to stay Jun 6 — 10:

Iwokrama Forest, Guyana — 1 night

One of the world's few remaining unspoiled tropical forests, Iwokrama Forest encompasses 3,700 sq km (1,400 sq mi) of lowland wilderness rainforest.
Kick off your visit on the 11th (Sat): take an exotic tour of Bushmasters.

To find maps, more things to do, where to stay, and more tourist information, read our Iwokrama Forest visit planner.

Traveling by combination of bus, flight, and car from Ciudad Del Este to Iwokrama Forest takes 18 hours. Alternatively, you can do a combination of car and flight. The time zone difference when traveling from Ciudad Del Este to Iwokrama Forest is minus 1 hour. On the 11th (Sat), wrap the sightseeing up by early afternoon so you can travel to Georgetown.
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Tours · Wildlife · Outdoors
Side Trip
Find places to stay Jun 10 — 11:

Georgetown, Guyana — 8 nights

Guyana's capital and main urban area, Georgetown represents the starting point for many visits to the country.
Georgetown is known for sightseeing, parks, and museums. Your trip includes some of its best attractions: get a taste of the local shopping with Perfumes Guyana, learn about winemaking at Pandama Retreat & Winery, snap pictures at Demerara Harbour Bridge, and hunt for treasures at Stabroek Market.

To find reviews, traveler tips, ratings, and more tourist information, you can read our Georgetown journey planner.

You can do a combination of taxi and flight from Iwokrama Forest to Georgetown in 8.5 hours. In June, daily temperatures in Georgetown can reach 85°F, while at night they dip to 78°F. Cap off your sightseeing on the 19th (Sun) early enough to travel back home.
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Shopping · Wineries · Museums · Historic Sites
Find places to stay Jun 11 — 19:

Colombia travel guide

4
Historic Sites · Landmarks · Beaches
Diverse in terms of landscapes, climates, and cultures, Colombia remains one of South America's least explored tourist destinations, overshadowed by its more popular southern neighbors. Combining the best of what the continent has to offer, a vacation in Colombia allows you to blend outdoor adventures with tours of picture-perfect cobblestoned towns dating back to the colonial era. Tourists on a Colombia holiday can easily hop from sun-kissed coastal spots to the hilly coffee-growing region, where thriving plantations quickly give way to a landscape of snow-covered volcanic peaks and the paramo--alpine ecosystems sheltering some of the rarest plants growing above the continuous forest line.
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Ecuador travel guide

4.5
Architectural Buildings · Landmarks · History Museums
With abundant opportunities to discover fascinating World Heritage Sites, a holiday in Ecuador remains among the most culturally enriching travel experiences. Home to the world's highest active volcano, this little country packs a big punch when it comes to tourist activities. Some of the most popular things to do in Ecuador include visits to its astonishingly biodiverse wilderness areas, home to some 1,500 bird species, 840 species of amphibians and reptiles, and nearly 20,000 plant species. Of course, the highlight of many Ecuador vacations is bound to be the Galapagos Islands, made famous by naturalist Charles Darwin. Aside from the stunning nature, Ecuador also boasts many historic cities filled with photogenic colonial-era churches, mansions, and plazas.
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Paraguay travel guide

3.8
Landmarks · Shopping Malls · Gift & Specialty Shops
Heart of South America
Divided in half by its eponymous river, Paraguay is a land of contrasts, especially between its lush eastern region where most of the population lives and the arid west, filled with rustic villages and old Jesuit colonies. Although under Spanish rule for three centuries and with a recent history of dictatorships and wars, Paraguay retained its native Guarani culture, with more than 80 percent of population of indigenous heritage. You'll find plenty of things to do in Paraguay, from touring cosmopolitan cities and quaint Jesuit colonies, to browsing affordable arts and crafts stores and sailing on rivers that crisscross the diverse natural landscape that makes up this landlocked nation.
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Guyana travel guide

3.6
Nature & Parks · Architectural Buildings · Museums
Land of Many Waters
A land of thick rainforest, expansive savannas, and lively Caribbean culture, Guyana is becoming more and more notable for its adventure and eco-tourism opportunities. Sightseeing in Guyana ranges from touring the colonial-era architectural gems of the historic capital, to hiking the verdant forest trails. Scenic waterfalls and mountaintops, laidback ranches, an array of tropical wildlife, and delicious Creole fusion cuisine await you on your Guyana holiday.
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